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Old 22-09-2007, 11:44 PM   #1 (permalink)
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Treatment of pneumothorax: "nitrogen washout"?

Im a HCA on a surgerical ward (we have alot of pneumothoraces). We've just had a new registrar start on the ward who suggested we use a technique of nitrogen washout (putting patient on high flow oxygen) for treatment of a small pneumothorax. It was the first time the technique has ever been used on this ward, the nurses said.

Can anyone explain to me what a 'nitrogen washout' is exactly? And why its so uncommonly used?
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Old 22-09-2007, 11:55 PM   #2 (permalink)
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Air is mostly nitrogen, right?

Well, if you have a pneumothroax while breathing room air, most of the volume in the pleural space is, logically, going to be Nitrogen.

By breathing 100% oxygen, you lower the level of Nitrogen within the alveoli and, thus, the nitrogen in the pleural space will diffuse across (down the gradient).

The volume of gas within the pnuemothorax should then fall. It won't resolve the pneuomothorax completely but it's a recognised treatment for small vol collections.
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Old 23-09-2007, 12:03 AM   #3 (permalink)
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Thanks Mark (avid reader of your blog btw )

My knowledge of anatomy is wrong I think.. because I thought the pleural space was a closed unit, and that there was no transport mechanism between alveoli and the space.
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Old 23-09-2007, 12:10 AM   #4 (permalink)
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There's always going to be a limited amount of gas exchange going on. Don't get me wrong, nitrogen washout is a crap way to treat a pneumothorax but it's always an option in those where you'd not bother treating anyway (ie, small vol of air in a healthy patient)
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Old 23-09-2007, 12:00 PM   #5 (permalink)
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presumably it works because nitrogen is either smaller than oxygen or more easily dissolved in the membrane so it diffuses faster than oxygen? otherwise wouldn't the gas volume remain the same and just change in composition because there would be diffusion both ways?

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Old 23-09-2007, 05:22 PM   #6 (permalink)
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I'm happy to admit that my physiology fails me at this stage and I can't explain why what you're proposing doesn't happen auden!

All I know is that nitrogen washout works (sort of!) to reduce small pneumothoraces. I imagine that the fact that oxygen is utilised when nitrogen isn't has something to do with it but I really don't know for certain.

What we need is a respiratory bod to give us the definitive answer. As a surgical house officer, I mainly concern myself with overloading post op patients...
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Old 23-09-2007, 06:37 PM   #7 (permalink)
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My guess would be because there is a higher pressure exerted on the air so the nitrogen, or any gas, is forced into the lungs (conc gradient allowing) more readily than oxygen, or any gas, out of the lungs into the pleural space.
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Old 24-09-2007, 02:43 AM   #8 (permalink)
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Quote:
Air is mostly nitrogen, right?

Well, if you have a pneumothroax while breathing room air, most of the volume in the pleural space is, logically, going to be Nitrogen.

By breathing 100% oxygen, you lower the level of Nitrogen within the alveoli and, thus, the nitrogen in the pleural space will diffuse across (down the gradient).

The volume of gas within the pnuemothorax should then fall. It won't resolve the pneuomothorax completely but it's a recognised treatment for small vol collections.
Half the answer's there. Putting someone on high flow oxygen lowers the nitrogen in the pleural space and replaces it with oxygen. Oxygen is absorbed more easily than nitrogen in the pleural space and thus the pneumothorax resolves quicker (1).

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Don't get me wrong, nitrogen washout is a crap way to treat a pneumothorax but it's always an option in those where you'd not bother treating anyway (ie, small vol of air in a healthy patient)
Er... wouldnt really call it crap. There is evidence that it does work. If I had a 25% spontaneous pneumothorax I'd much prefer a week of O2 therapy than an FY1 sticking a needle/drain into my pleural space to save a few days (I put in around 20 drains as a PRHO in resp med, unsupervised after 2 if I recall correctly). ALL patients with pneumothoraces back when I worked on a resp firm went on high flow O2 if there was no contraindication. Every little helps! In small pneumothoraces with no breathlessness, BTS guidelines suggest discharge can be considered without any interventions with early follow up and advice to seek help if any worrying features develop (2). So your registrar's conservative management in this case is perfectly valid.

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Im a HCA on a surgerical ward (we have alot of pneumothoraces). We've just had a new registrar start on the ward who suggested we use a technique of nitrogen washout (putting patient on high flow oxygen) for treatment of a small pneumothorax. It was the first time the technique has ever been used on this ward, the nurses said.

Can anyone explain to me what a 'nitrogen washout' is exactly? And why its so uncommonly used?
Because you're on a surgical ward where sexy drains would be reached for over a not so sexy oxygen mask? (I'm surgically inclined so I can take the piss a little!). I doubt it's the first time it's been used on that ward anyway (since the evidence is over 35 years old), it's just not often called "nitrogen washout" and people (particularly busy nurses who have other things to worry about) often don't understand the reason behind high flow O2 in a patient with a pneumothorax past the obvious.

1. Northfield TC. Oxygen therapy for spontaneous pneumothorax. BMJ
1971;4:86-88.
2. M Henry et al. BTS guidelines for the management of spontaneous pneumothorax. Thorax 2003;58:ii39.

Last edited by Touche; 24-09-2007 at 03:56 AM.
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Old 25-09-2007, 08:47 PM   #9 (permalink)
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cheers Touche - that's an excellent explanation

And also cheers to Mark who made me look oh so competent the other day when we did this for a patient and the SpR asked why we were giving high flow O2 to someone with a pneumothorax (I'm on a resp firm!)
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